Random Forest model reveals the interaction between N6-methyladenosine modifications and RNA-binding proteins
Summary: RNA-binding proteins (RBPs) have critical roles in N6-methyladenosine (m6A) modification process.We designed a Random Forest (RF) model to systematically analyze the interaction among RBPs and m6A modifications by integrating the binding signals from hundreds of RBPs.Accurate prediction of m6A sites demonstrated significant connections bet